Structure and organization of regulatory machinery in cancer cells.
The organization and location of machinery that controls genes is modified during the
onset and progression of cancer.

THE DISEASE

About a third of humans develop cancer in a lifetime. Cancer starts as an abnormal cell which grows with time into a mass of cells, some of which can spread to other. locations in the body (metastasize), where they grow and upset normal bodily functions. It is one of the most frequent causes of human death. The rate of death varies greatly for different types of cancer. Lung and pancreatic cancer are the worst, usually fatal within a year. But not all cancers are fatal: Only one-fifth of breast cases result in death. Successful treatments utilize surgery, radiation, drugs,
and immunology.